Pentoxifylline is a hemorheologic
agent used to treat
diseases and conditions in which improved
circulation is beneficial.Add this item to your cart:
**Note: This product requires a veterinarian's prescription to purchase.At checkout you will need to provide your
veterinarian's FAX or email address. We will then send him or her a prescription verification that he or she
will need to sign and return before we can ship you this product.
Dosage and Administration:
Follow your Veterinarian's prescription dosage and instructions
For dogs, the dose of pentoxifylline
as adjunctive therapy for ulcerative
dermatosis is 400 mg PO sid or every
other day if vomiting is a problem.
For adjunctive treatment of dermatomyositis,
the dose is 10 mg/kg PO sid
or every other day. Two to 3 months
of therapy may be needed to see improvement.
9 For adjunctive treatment
of ear margin seborrhea, the recommended
dose of pentoxifylline is 400
mg/day PO unless the dog weighs less
than 10 kg in which case 200
mg/day is administered.
In horses, a dose of 8.5 mg/kg PO
bid is recommended for reducing the
cytokine effects in endotoxemia. For
the treatment of navicular disease, 6
g/day PO for 6 weeks should be used.3
* Pentoxifylline should be
given with a small amount
of food or a treat to lessen
* Give your pet only the dose
recommended by your
If your pet shows signs of
agitation, restlessness, or a
rapid heartbeat while taking
pentoxifylline, contact your
Because pentoxifylline may
interact with other drugs,
contact your veterinarian
before giving any other
Warfarin use with pentoxifylline
may result in an increased risk of
Concomitant use of other methylxanthines
theophylline may lead to increased
blood levels and toxicity of
one of the methylxanthines.
Patients should be monitored for
efficacy of treatment. Because pentoxifylline
is a methylxanthine, dogs and
cats in particular should be monitored
for such adverse reactions as central
nervous system or cardiovascular stimulation.
Safety in Pregnant pets is unknown and should not be used in nursing mothers.
Use with caution with Pet's with the following conditions:
Pre existing seizure disorders, bleeding disorders, GI ulcers, liver or kidney insufficiency or if pet has had a past allergic reaction to pentoxifylline, theophylline or other xanthines including aminophylline or caffeine.
Possible Side Effects:
Medically and scientifically documentation has stated that this medication does affect the GI tract, vomiting and diarrhea has been warranted by oral dosage. Due to its anti-coagulate effect on the bloodstream, retinal or cerebral bleed can occur. If this medication is prescribed, be vigilant and watch for signs that may be a health concern for your pet.
For Your Pet