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Primidone is used to for long-term control of convulsions, seizures, and epilepsy in dogs.
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Item# Size/Desc Qty Price
50 mg per tablet
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This item requires a RX
50 mg 100 count bottle
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This item requires a RX
250 mg per tablet
This item requires a RX
250mg 100 count bottle
This item requires a RX

**Note: This product requires a veterinarian's prescription to purchase.At checkout you will need to provide your veterinarian's FAX or email address. We will then send him or her a prescription verification that he or she will need to sign and return before we can ship you this product.

Dosage and Administration:


All weights The usual dose in dogs is 2.3-6.8 mg per pound of pet&rsquos body weight per day in 2 or 3 divided doses. Primidone can be given with food. Allow plenty of water for your pet to drink

Primidone is a prescription medication used to control seizures and epilepsy in dogs. It is believed that Primidone alters the chemical impulses in the brain that cause seizures.
Primidone should not be given to cats.
Primidone may cause drowsiness and dizziness.

Do not stop giving this medication. It is important to continue giving Primidone to prevent seizures from recurring.


Primidone should not be used in pregnant or nursing animals. Other drugs, as well as vitamins and supplements, may have an adverse interaction with Primidone, so disclose to your veterinarian what other products you are giving to your pet. Primidone may cause drowsiness, dizziness, hives, swelling or other side effects.
Contact your vet at the onset of any of abnormal physical or behavioral change in your pet. It is very important not to miss giving your pet a dose, as this can cause a seizure.
Do not give primidone to dogs allergic to Phenobarbital. Primidone should not be given to cats. Primidone may cause dizziness or drowsiness. Use caution when giving other medications that may cause dizziness or drowsiness.

Possible Side Effects:

If your pet develops any of the following serious side effects, stop giving primidone and seek emergency veterinary medical attention an allergic reaction difficulty breathing, closing of the throat, swelling of the lips, tongue, face, or hives a rash worsening of seizures fever. Other less serious side effects may occur. Continue to give primidone and talk to your veterinarian if your pet experiences dizziness, poor coordination, or drowsiness blurred vision irregular back and forth movements of the eyes or nausea and vomiting. Side effects other than those listed in this guide may also occur. Talk to your veterinarian about any side effect that seems unusual or that is especially bothersome to your pet.

What drugs will affect primidone:

Acetazolamide Diamox, carbamazepine Tegretol, ethosuximide Zarontin, and methsuximide Celontin may decrease the effects of primidone and require a higher primidone dose. Phenytoin Dilantin, ethotoin Peganone, mephenytoin Mesantoin, and isoniazid may increase the effects of primidone and require a lower primidone dose. Carbamezepine Tegretol blood levels may increase when given with primidone. The carbamazepine dose may need to be adjusted lower. CNS depressants, valproic acid and chloramphenicol may increase the effect of primidone. Primidone may decrease the effect of coumadin, corticosteroids such as prednisone, beta blockers such as atenolol, theophylline and metronidazole. Use with caution when giving primidone with furosemide, griseofulvin or rifampin.