Vetmedin is indicated for the management of the signs of mild, moderate, or severe congestive heart failure in dogs due to atrioventricular valvular insufficiency AVVI or dilated cardiomyopathy DCM. This medication increases the pumping action of the heart and opens up blood vessels. Vetmedin is indicated for use with concurrent therapy for congestive heart failure e.g., furosemide, etc. as appropriate on a case-by-case basis.
Dosage and Administration
Vetmedin should be administered by mouth at a total daily dose of 0.23 mg/lb 0.5 mg/kg body weight. The total daily dose should be divided into 2 portions that are not necessarily equal, and the portions should be administered approximately 12 hours apart. Many dogs will consume the tablets voluntarily if offered by hand.
Warnings, Side Effects and Drug Interactions
Vetmedin is only for use in dogs with clinical evidence of heart failure. However, it should not be given in cases of a thickened, enlarged heart, narrowing of the aorta, or any other clinical condition where an increase in the pumping of the heart is inappropriate for functional or anatomical reasons. The safety of Vetmedin has not been established in dogs with asymptomatic heart disease or in heart failure caused by etiologies other than AVVI or DCM.
The safe use of Vetmedin has not been evaluated in dogs younger than 6 months of age, dogs with congenital heart defects, dogs with diabetes mellitus or other serious metabolic diseases, dogs used for breeding, or pregnant or lactating dogs.
Adverse reactions seen occasionally in dogs treated with Vetmedin include: reduced appetite, lethargy, diarrhea, vomiting, breathlessness, weakness, unsteady gait, fainting, coughing, fluid retention, including fluid on the lungs, kidney disease, further heart damage, weight loss, trembling, seizures, itching, increased drinking and urination, liver damage, blood cell changes, diabetes mellitus and sudden death,. However, many of these are also common signs seen in animals with heart failure, so may be a symptom of the disease itself rather than the medication.
VetMedin, VetMedin for Dogs
Vetmedin has been used safely in dogs concurrently receiving heart medications including furosemide, digoxin, enalapril, atenolol, spironolactone, nitroglycerin, hydralazine, diltiazemas well as antiparasitic products including heartworm prevention, antibiotics metronidazole, cephalexin, amoxicillin-clavulanate, fluoroquinolones, topical ophthalmic and otic products, famotidine, theophylline, levothyroxine sodium, diphenhydramine, hydrocodone, metoclopramide, and butorphanol, and in dogs on sodium-restricted diets.
Not for use in humans. Keep this and all medications out of reach of children. Consult a physician in case of accidental ingestion by humans.