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Slentrol is the first prescription weight-loss medication for dogs
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Item# Size/Desc Qty Price
5mg oral solution, 20ml
This item requires a RX
5mg oral solution, 50ml
Item qualifies for FREE SHIPPINGThis item requires a RX
5mg oral solution, 150ml
Item qualifies for FREE SHIPPINGThis item requires a RX

**Note: This product requires a veterinarian's prescription to purchase.At checkout you will need to provide your veterinarian's FAX or email address. We will then send him or her a prescription verification that he or she will need to sign and return before we can ship you this product.

SLENTROL is a prescription medicine to help obese dogs lose weight. It should be used as part of an overall weight loss program which includes diet and exercise.


SLENTROL works inside the small intestine of the dog. It keeps some of the fat from being absorbed into the body, so the dog senses that it is full and eats less at each meal. A less-hungry dog takes in fewer calories, which leads to weight loss.

Unlike human weight-loss drugs, SLENTROL is not associated with undesirable side effects such as oily discharges and excessive gas.

The result? Your dog could lose, on average, 3% of its weight every month through the medically appropriate approach of gradual, sustained weight loss over time.

Results with SLENTROL:

Dependable weight loss you can count on:

Out of 141 dogs completing a 4-month study, almost all of the dogs taking SLENTROL lost weight. The average weight loss was 3% each month. By the end of the study, more than half the dogs had lost at least 11% of their body weight and that's an amount that has been proven to show real health benefits.

Of course, the time it takes for your dog to lose weight depends on several factors. Since each dog is different, you need to bring the dog to the veterinarian once a month, so the weight loss can be measured and, if needed, the dose of SLENTROL adjusted.

How to Use SLENTROL:

Once-a-day SLENTROL is easy to give

A veterinarian must prescribe SLENTROL. It should not be available to you in any other way. SLENTROL is a once-a-day, clear, oil-based liquid that comes with an easy-to-use oral dosing syringe. When giving SLENTROL at home, you can give it on a healthy treat, with a small amount of food, or directly in your dogs mouth.

Always use the oral dosing syringe that comes with SLENTROL, which has been designed to help you give the right dose to your dog and is made specifically for use with an oil-based liquid. Other applicators or syringes may cause you to give the wrong dose and may react with the liquid medication.

Be sure to wipe the oral dosing syringe after each use. Use a clean dry cloth or disposable towel. Do not let any water get into the syringe or into the SLENTROL solution bottle.

Your veterinarian will determine the right dose for your dog at each visit and explain how to use the oral dosing syringe. The dose of SLENTROL that you give your dog each day is based on your dogs current weight and on how fast or slowly your dog loses weight. Always follow the directions and give SLENTROL the correct way. If you have any questions about giving your dog SLENTROL, be sure to ask your veterinarian.

The SLENTROL Treatment Plan:

Losing weight won't happen overnight. It may take a few weeks before you start seeing a difference in your dog, and several months before your dog reaches the desired weight. But keep in mind that SLENTROL is more than just medicine. It is really a plan to help your dog lead a healthier life!

2 treatment phases with SLENTROL

SLENTROL provides a medically appropriate approach to weight management for obese dogs.

Weight-Loss Phase. This first phase lasts as long as it takes to reach the desired weight set by your veterinarian. Monthly weight checks are necessary to track progress and adjust the dose, if needed.

Weight-Management Phase. Medication continues, and the dose may be adjusted to help keep your dog close to the desired weight. You should continue the monthly visits and begin measuring the amount of food your dog is actually eating.

After treatment with SLENTROL. Continue the lifestyle adjustments you've made and measuring the amount of food and keeping up the exercise to maintain a healthy weight for your dog.

Your dog may already be taking SLENTROL. Or, you may be considering treating your dog with the medication. Either way, if you have an obese dog, SLENTROL gives you and your veterinarian a chance to improve the health of your dog and improve your dog's quality of life.


Keeping Track

We have created a useful tool to help you keep track of what happens to your dog while taking SLENTROL and journal of the changes in activity and behavior that could occur.

The Owner Journal gives you the ability to list daily events that are part of your dog&rsquos life, plus a way to note positive events such as more energy and playfulness that often happen to dogs who take part in the SLENTROL program.

Some of the things you can include in your journal:
  • Number of walks and extended play times
  • Amount of food your dog is eating measured in cups
  • Any positive behavior changes, such as your dog becoming
    more playful
  • General impressions of your dog&rsquos activity level

Keeping track of your dogs progress can help you stay on top of your dogs health, so print an Owner Journal every month and create a custom progress report for your dog. It is great to have a record of the changes taking place! 

To print an Owner Jounral click below: https://www.slentrol.com/docs/Owner_Journal.pdf

Frequently Asked Questions 
reference Pfizer

Why is it important for my dog to lose weight?

Obesity in dogs is an important medical condition with serious health consequences. Dogs that are obese have more difficulty with their joints arthritis, breathing and heart problems. They also are more likely than normal weight dogs to get infections on their skin and to have problems with anesthesia and surgery.

Dogs that are obese don't run and play as much as dogs who carry less extra weight. They seem to have less fun than other dogs because of this. They often have trouble going up stairs, getting into cars and just simply walking down the street.

Managing obesity in your dog is not a matter of looking good its about managing serious health consequences. Controlling obesity can prevent some serious health consequences and improve your dog&rsquos quality of life.

How does SLENTROL work?
SLENTROL is a medicine called an MTP inhibitor. It works by preventing some of the fat your dog eats from being absorbed into the body. When that happens a message is sent to your dog&rsquos brain that tells him he's full. In fact, one of the first things you'll notice is that your dog won't want to eat as much as before. The weight loss happens because your dog is eating less food.

How is SLENTROL given to my dog?
A veterinarian must prescribe SLENTROL. It should not be available to you in any other way. SLENTROL is available only as clear oil based liquid and comes with an easy-to-use syringe. SLENTROL is given once a day. When giving SLENTROL at home, you can give it on a healthy treat, with a small amount of food, or directly in your dog's mouth. You should always use the syringe that comes with SLENTROL. The syringes have been made to help you give the right dose to your dog. The syringes are also made to be used with an oil based liquid. Using other syringes may cause you to give the wrong dose and may react with the liquid medication.

The dose of SLENTROL is based on your dogs current weight, and how fast or slowly your dog loses weight. There are two phases with SLENTROL treatment, a Weight Loss phase and a Weight Management phase. Your veterinarian will determine the right dose for your dog every month after a weigh-in. You should expect that the dose will change after some visits and not at others. In the Weight Loss phase the goal is to have your dog lose enough pounds to reach a desired weight. Your dog won't want to eat as much food and that's what will cause the weight loss. You won't have to worry so much about how much food is in the bowl because s/he probably won't eat it all. During the Weight Management phase the goal is to find out how many calories your dog needs to maintain the desired weight. You'll be asked by your veterinarian to measure how much your dog eats during this time. Later on after you stop giving SLENTROL this will be the amount of food you give to your dog. Only through diet and exercise can you help him/her stay at the healthier weight long term.

Always follow the directions and give this treatment the right way. If you have any questions about giving SLENTROL to your dog, ask your veterinarian.

When should SLENTROL be used in dogs?
Many dog owners don't know their dogs are overweight or obese. In fact some information suggests that as many as 17 million dogs in the US are overweight or obese. Experts tell us that dogs 20% or more over their ideal weight are obese and that obesity in dogs is an important medical condition that has serious health consequences. If your veterinarian determines that your dog is obese, SLENTROL may be used as part of an overall weight loss program that includes diet and exercise.

Will SLENTROL help my dog?
Most dogs will lose weight when SLENTROL is used. You can expect that your dog will lose weight gradually. Some dogs lose weight quickly and others lose weight very slowly. Your veterinarian will keep track of how much weight your dog is losing and adjust the dose of SLENTROL to help reach the desired weight for your dog.Weight loss experts have given guidelines for what is a safe and effective amount of weight for dogs to lose over a period of time. Your veterinarian understands these guidelines and will help you follow them.

SLENTROL was specifically designed so that the dose could easily be adjusted for your dog, that's why its important to visit your veterinarian as often as directed. You should not adjust the amount of SLENTROL you give your dog without instructions from your veterinarian.

How do I know the ideal body weight of my dog?
Dogs come in different sizes and shapes so its hard to put ideal dog weights on a chart. Your veterinarian can work with you to decide what the desired target is for your dog&rsquos weight loss program. Some veterinarians will prefer to target a specific weight, others will use a percentage of body weight or a body condition score BCS. Some experts use a dog's body weight at 1 to 2 years of age a guide for ideal weight. Regardless of the weight loss program or target used, any weight loss in an obese dog is considered good.

Do I have to change my dogs diet while receiving SLENTROL? What about treats?
You don't have to change your dogs diet as long as you are using a nutritionally complete and balanced commercial maintenance diet. Your veterinarian can help you find out if the food you're using fits this description. Some home-made diets may not have enough vitamins, so those diets are not recommended. In addition some restriction diets may not be suitable to offer during the weight loss phase. As with any weight loss program only healthy treats should be given to your dog and in reasonable amounts.

When should I feed my dog and give SLENTROL?
SLENTROL may be given with or without a meal, but should not be mixed in with a full meal because your dog may not eat all of it. SLENTROL may be given in the morning or evening, whichever is best for you and your dog. Pick a schedule so that you can be sure to give the medication once every 24 hours.

Is there any follow-up I need to do?
It is important that you follow your veterinarians instructions for monthly weigh-ins because the dose of SLENTROL will be based on your dogs rate of weight loss. This will also allow you and your veterinarian to review your dogs diet and exercise progress and make any necessary adjustments. Some veterinarians may also recommend blood tests during the course of the weight loss program. Be sure to follow these directions as well.

How long do I have to give SLENTROL to my dog?
You and your veterinarian will decide your dogs desired weight. Regular monthly monitoring will help you to know when this goal is reached. Once the desired weight has been reached you will keep your dog on SLENTROL while you learn how to keep his/her weight at that goal. This phase, called the Weight Management phase is very important. It will help you know how much food and exercise your dog needs daily in order to stay at a healthier weight. While SLENTROL is a very effective tool to help you manage your dogs obesity, keeping your dog healthy over time will depend on finding and sticking to the right balance of diet and exercise.

What will happen when I stop giving my dog SLENTROL?
SLENTROL works only while it is being given to your dog. Once you stop SLENTROL your dogs appetite will return to normal within a day or two. Some dogs may even seem hungrier just after they stop getting SLENTROL than they did before. SLENTROL, or any other method of weight loss, is not a permanent cure for obesity. Thats why its important to stick with the program that you develop while using SLENTROL in the Weight Management phase.When you are finished with the Weight Management phase you should know how much food your dog needs to maintain his/her desired weight. More often than not this will mean that you will feed your dog a smaller portion of food than s/he used to eat. This is one of the main goals of the program that will help you and your dog be successful in maintaining his/her desired weight in the long run. If you return to the habits that allowed your dog to become obese your dog will gain weight again. A healthier lifestyle includes, but is not limited to, providing your dog a nutritionally-balanced diet, offering only healthy low calorie treats and ensuring that your pet receives enough exercise on a daily basis. Your veterinarian is the best person to help you develop a healthier lifestyle for your dog.

Does SLENTROL have side effects?

SLENTROL is generally well tolerated, however side effects have been reported. The most common side effect is vomiting, especially during the first month of treatment and when the dose is increased. Dogs that vomit from SLENTROL usually feel good in every other way. Dogs that vomit from SLENTROL typically only vomit once or twice and the vomiting goes away on its own while the dog is still taking the medication. Ask your veterinarian about how to manage this if vomiting is a problem for your dog. Some dogs may seem tired, have diarrhea, or lose their appetite completely but these side effects are less likely. You should contact your veterinarian if any of these signs persist for more than 2 days.

Other side effects can include increases in your dogs liver enzymes. These changes can only be found through blood testing. When caused by SLENTROL these liver enzyme increases are temporary and most often return to normal on their own while the dog is taking SLENTROL. Some veterinarians may choose to monitor these enzymes while your dog is on SLENTROL. Your veterinarian can discuss these blood tests with you.

Call your veterinarian if you notice any unexpected changes in your pet while taking SLENTROL.

Can SLENTROL be used for all dogs that are obese?
Before any dog is started on therapy with SLENTROL, it is important to try to find out if there are any medical causes of the obesity. While most dogs become obese because they eat too much and exercise too little, some dogs become obese because of another problem like a hormone disorder. If your dog has another problem your veterinarian will want to manage it before starting a weight loss program that includes SLENTROL. There are some medicines that your dog shouldn't take while on SLENTROL so be sure to tell your veterinarian about any products you give your dog including prescription and over-the-counter medications.

Who should not take SLENTROL?
SLENTROL is not for use in dogs taking long-term corticosteroids or dogs with liver disease. SLENTROL should not be given to young growing dogs, pregnant dogs, or dogs used for breeding. Be sure to tell your veterinarian if your dog is pregnant or nursing, or if you are planning on breeding your dog. SLENTROL is not for use in cats as serious liver issues could develop. SLENTROL is not for use by humans under any circumstances.

What else should I know about SLENTROL ?
SLENTROL is not a cure for obesity. SLENTROL should be part of an overall weight loss program that includes diet and exercise. Successful long-term weight management requires behavior changes that last a lifetime. Monitoring your dogs progress is important.

What should I do if I miss a dose? Give too much? When do I re-dose?
You should call your veterinarian if you miss a dose or change the dose from what was recommended.

How should SLENTROL be stored?
SLENTROL should be kept in the original container at room temperature 59°-86° F. Do not get water in the bottle of SLENTROL as it may cause discoloration and allow bacteria to grow. Keep the syringe dry so that you don't get water in the bottle.


  • SLENTROL is for dogs only
  • SLENTROL must be prescribed by a veterinarian
  • Keep out of reach of children

A learning tool brought to you by Pfizer Animal Health
Slentrol is a registered trademark of Pfizer Animal Health.  The information provided on this website is for educational purposes only and is intended to be a supplement to, and not a substitute for, the expertise and professional judgment of your veterinarian. We reference Pfizer as the source for our information, you may research this product further at the Pfizer Animal Health webpage:  https://www.slentrol.com.  You should always consult your own veterinarian for specific advice concerning the diagnosis, and treatment of your pet. As stated the information provided is for educational purposes to aid you in purchasing your pet's medication, it is not a substitute for a veterinary exam, nor does this information suggest that this medication will be tolerated by your pet or that your pet will not experience side effects.
Note: Any trademarks are the property of their respective companies