Cosequin ASU from Nutramax Laboratories, Inc. is a
superior joint health supplement in a tasty powder for
horses that goes beyond standard joint supplements.
It contains NMX1000®* avocado/soybean
unsaponifiables ASU, MSM methylsulfonylmethane,
FCHG49®* glucosamine hydrochloride, and TRH122®*
With this combination of active
ingredients, Cosequin ASU is the most complete joint
support supplement available for horses.
What role do the glucosamine hydrochloride
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What is ASU?
ASU stands for avocado/soybean unsaponifiables, derived from
avocados and soybeans. Studies using cartilage cells have
shown that it lowers the expression or production of several
compounds involved in the process of cartilage breakdown in
joints. ASU complements the positive effects of the glucosamine
and chondroitin sulfate in Cosequin®ASU. The glucosamine in
Cosequin ASU is synergistic with chondroitin sulfate and has
been shown in cartilage cell studies to be synergistic with ASU.
Having ASU in the Cosequin ASU formula is especially beneficial
as NMX1000® avocado/soybean unsaponifiables, FCHG49®
glucosamine hydrochloride and TRH122® chondroitin sulfate
together were shown in cell studies to be more effective than
the combination of glucosamine and chondroitin sulfate alone at
inhibiting expression of several agents involved in the breakdown
Why is MSM included in the formula?
Although clinical data on MSM is limited, many veterinarians and
trainers recommend the use of MSM in the management of joint
health. MSM is an organic source of sulfur, a compound used
by cartilage. Cosequin ASU provides a joint health supplement
formula for those individuals that would like to additionally
supplement with high purity MSM.
What is meant by broad spectrum?
Broad spectrum means that the ingredients support cartilage
health via many pathways. As mentioned earlier in this brochure,
the ingredients inhibit compounds and enzymes in the joint that
contribute to cartilage breakdown while also supporting cartilage
How is Cosequin®ASU different from other supplements?
Cosequin ASU contains the ingredient ASU along with the optimal
amounts of glucosamine and chondroitin sulfate that your horse
needs. ASU works along with glucosamine and chondroitin sulfate to
support your horse's joints. In fact, the combination of glucosamine/
chondroitin sulfate plus ASU has been shown to work better in
cartilage cell research than glucosamine/chondroitin sulfate alone.
Cosequin ASU has the further addition of high purity MSM. Some
veterinarians suggest using MSM to help manage joint health.
Are there any safety concerns with Cosequin ASU?
Cosequin ASU has been evaluated in a safety study in horses, and no
adverse effects were noted from administration. There are no known
contraindications or known interactions between Cosequin ASU and
any drug or nutritional supplement.
Can Cosequin ASU be given to a pregnant mare?
No studies have been completed that specifically address the use
of Cosequin ASU during pregnancy. Use of Cosequin ASU during
pregnancy should be an individual decision made in consultation with
Can Cosequin ASU be used on a competition day?
Cosequin ASU contains supplement ingredients for assisting joint
health. It is best to check with your appropriate authority regarding its
regulations or restrictions on supplement usage.
How do I administer Cosequin ASU?
Cosequin ASU's tasty powder can be added to your horse's feed by
following the administration table below.
Administration as a supplement for horses:
Initial 2-4 weeks:
Under 600lbs 1 scoop daily
600lbs to 1200lbs 2 scoops daily
Over 1200lbs 3 scoops daily
Under 600lbs 1/2 scoop daily
600lbs-1200lbs 1 scoop daily
Over 1200lbs 1-2 scoops daily
Allow 2-4 weeks initially to note a response, though some
horses may respond sooner. Once a positive response is
seen, the number of scoops may be reduced to the level
that keeps your horse comfortable. When lowering the
number of scoops, observe your horse closely. If your
horse's comfort level appears to decrease, the initial
administration amount should be resumed for an additional
2 weeks before trying the long-term administration level
Once consistent improvement at the long-term
administration level has been seen, amount may be further
reduced to the minimum necessary to keep your horse
comfortable. While the administration guide provides the
number of scoops recommended to help the average horse,
an individual horse's needs may vary. Horses on a longterm
administration level can be increased back to the initial
level at any time as needed e.g., prior to or during an event
or strenuous exercise. A long-term administration level can
also be used on healthy horses to help support their joints.
At any time, the number of scoops may be increased if
What response should I see in my horse
when giving Cosequin®ASU?
Prior to starting Cosequin ASU, you may have noticed
unevenness of gait, reluctance to take or change a lead,
or shortness of stride, which may be early indicators of
cartilage breakdown. After starting administration with
Cosequin ASU, observe your horse closely, and notice
whether your horse becomes more comfortable doing
those activities he/she seemed reluctant doing or had some
trouble doing previously. Changes in your horse's comfort
level may occur gradually. Please allow time for your horse
to respond. As noted above, it may take 2-4 weeks to see
improvement, though some horses may respond sooner.
My veterinarian has also recommended an
injectable joint product. Why?
Cosequin ASU helps to minimize ongoing joint wear and tear
by supporting joint cartilage production and by inhibiting
enzymes and mediators involved in cartilage breakdown.
Horses will usually respond to Cosequin ASU within 2-4
weeks, sooner in some horses. In those cases in which a
more immediate response is desired, your veterinarian may
initially recommend an injectable product.
For Your Pet